E-Prescribing Companion Guide
Build and Support E‑Prescribing Transactions
The E-Prescribing Companion Guide provides detailed technical guidance for implementing and supporting E-Prescribing transactions on the Surescripts network. Use this guide when building, certifying, integrating, or troubleshooting E-Prescribing solutions.
This guide supplements the NCPDP SCRIPT Standard by documenting Surescripts-specific requirements, Application Certification Requirements (ACRs), and implementation best practices.
Note: This is early adopter documentation. Information is subject to change.
Section Descriptions & Links
Use the section descriptions below to understand how the guide is organized and where to find what you need.
Overview of E‑Prescribing capabilities, message types, and reference documentation
Overview of integration, certification, and production processes
Understand rules and expectations that apply across all E‑Prescribing message types
Message flow, structure, and best practices
Data element definitions, conditions, and business rules
How elements are used in workflows, including usage patterns and data quality guidance
Summary of all Application Certification Requirements referenced throughout the guide
Message ExamplesMessage Examples
Sample message format demonstrating structure, required elements, and expected usage
RxChange workflows for prior authorization, including alternate routing scenarios
Error codes, troubleshooting guidance, and best practices to resolve common issues
Message continuity services, including retry, queuing, and fax failover
Legal disclaimers covering guide usage, examples, and intellectual property
Key Sections by Role
Access Onboarding and Developer Tools
If you’re looking for onboarding resources, developer tools, or related E-Prescribing products, start with the E-Prescribing home pageE‑Prescribing home page.
- Get started with prerequisites, onboarding guidance, and connectivity setup
- Access implementation tools like Workbench, Message Tester, and Certification Tester
- Find upgrade guidance, documentation links, and support resources